German Center for Neurodegenerative Diseases

c/o Institute of Cognitive Neurology and Dementia Research
Otto-von-Guericke University Magdeburg
Leipziger Str. 44
39120 Magdeburg, Germany
Phone: + 49 391 67 250 58

Email: matthew.betts@dzne.de

Research Experience

Publications

Original research publications

Betts MJ, Acosta-Cabronero J, Cardenas-Blanco A, Nestor PJ, Düzel E (under review). High-resolution in vivo characterization of the aging human brain using simultaneous quantitative susceptibility mapping (QSM) and R2* measurements at 7 Tesla.

Acosta-Cabronero J, Betts MJ, Cardenas-Blanco A, Yang S, Nestor PJ (2015). In vivo MRI mapping of brain iron deposition across the adult lifespan. J.Neurosci. (in press)

Betts MJ, O’Neill M, Duty S (2012). Allosteric modulation of the group III mGlu receptor 4 provides functional neuroprotection in the rodent 6-OHDA model of Parkinson’s disease. Br J Pharmacol. Aug;166(8):2317-30

Broadstock M, Austin P, Betts MJ, Duty S (2012). Antiparkinsonian potential of targeting group III metabotropic glutamate receptor subtypes in the rodent substantia nigra pars reticulata.  Br J Pharmacol. Feb;165(4b):1034-45

Austin P, *Betts MJ, Broadstock M, O’Neill M, Mitchell S, Duty S (2010). Symptomatic and neuroprotective effects following activation of nigral group III metabotropic glutamate receptors in rodent models of Parkinson’s disease. Br J Pharmacol. Aug;160(7):1741-5

* Denotes co-first author

Book chapters

Düzel E, Guitart-Masip M, Maaß A, Haemmerer D, Betts M, Speck O, Weiskopf N, Kanowski M (2015). Midbrain fMRI: Applications, limitations and challenges

Conference proceedings

23^rd International Society for Magnetic Resonance in Medicine Annual Meeting, Toronto, Canada
Acosta-Cabronero J, Betts MJ, Cardenas-Blanco A, Yang S, Speck O, Nestor PJ (2015).
QSM standardisation routine for unbiased whole-brain analysis

13^th International Conference on Alzheimer’s and Parkinson’s Disease, Nice, France
Betts MJ, Liepelt-Scarfone I, Maaß A, Glanz W, Galatzky I, Berg D, Düzel E (2015). Impaired long-term memory for neutral but not emotionally negative stimuli in subjects at risk of Parkinson’s disease

Heider M, Betts MJ, Pertzov Y, Husain M, Düzel E (2015). Working memory binding in ageing: a VBM analysis of structural changes in low and high performing elderly individuals

XIII Magdeburg International Neurobiological Symposium, Magdeburg, Germany
Krauel K, Haynes JD, Heinze HJ, Tegelbeckers J, Pietro L, Perosa V, Breitling C, Guitart-Masip M, Düzel E, Bonath B, Flechtner HH, Betts MJ (2015). Pavlovian congruency in healthy development and attention deficit hyperactivity disorder (ADHD)

Dallas Aging and Cognition Conference, Dallas, USA
Betts MJ, Maaß A, Acosta-Cabronero J, Düzel E (2015). Striatum predicts memory bias for emotionally negative stimuli in young but not elderly adults

Annual Meeting of the Organization for Human Brain Mapping, Hamburg, Germany
Betts MJ, Kaufmann J, Heidel J, Lützkendorf R, Cardenas-Blanco A, Düzel E (2014). Connectivity-based parcellation of the SN/VTA using diffusion tensor imaging at 7 tesla

Maaß A, Betts M, Berron D, Düzel E (2014). 7T fMRI of SN/VTA, locus coeruleus & hippocampus during emotional & reward-related memory encoding

43^rd Annual Meeting of the Society for Neuroscience, San Diego, CA, USA
Betts MJ, Kaufmann J, Heidel J, Düzel E (2013). The effects of MR field strength on connectivity-based segmentation of the SN/VTA using diffusion tensor imaging at 3 and 7-tesla

40^th Annual Meeting of the Society for Neuroscience, San Diego, CA, USA
Betts M, O’Neill M, Mitchell S, Duty S (2010). Selective activation of the mGlu4 but not mGlu7 group III metabotropic glutamate receptor provides functional neuroprotection in the rat 6-OHDA model of Parkinson’s disease.

XVIII WFN Congress on Parkinson’s Disease and Related Disorders, Miami, USA
Betts M, O’Neill M, Mitchell S, Duty S (2009). Allosteric modulation of group III metabotropic glutamate receptor 4: a potential neuroprotective approach for the treatment of Parkinson's disease. Parkinsonism and Related Disorders 15(Suppl 2):S121

British Pharmacological Society, Winter Meeting, London, UK
Betts M, O’Neill M, Mitchell S, Duty S (2009). Supra-nigral administration of an mGlu4 receptor allosteric potentiator protects against histological and functional deficits in the 6-OHDA lesion rat model of Parkinson’s disease.

6^th International Meeting on Metabotropic Glutamate Receptors, Taormina, Sicily
Betts M, O’Neill M, Mitchell S, Duty S (2008). The group III mGlu receptor agonist L-AP4 affords both neurochemical and functional neuroprotection against a 6-hydroxydopamine lesion of the substantia nigra in rats. Neuropharmacology 55: 585-638(9)